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This is where bioavailability becomes the most important factor

Iodolipids have been found to inhibit DUOX (generating H 2 O 2 ) and adenylyl cyclase, suggesting that they are involved in regulatory actions of I in the thyroid via H 2 O 2 [114]

ACSL4 can catalyze the esterification of PUFAs in phospholipids on cellular membranes and enhance ferroptosis sensitivity to lipid peroxidation (Zhang et al., 2025c)

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